AN IN SILICO HIGH-THROUGHPUT SCREEN IDENTIFIES POTENTIAL SELECTIVE INHIBITORS FOR THE NON-RECEPTOR TYROSINE KINASE PYK2

An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

Tomer Meirson, Abraham O Samson, Hava Gil-Henn Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel Abstract: The non-receptor tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell migration, proliferation, and survival.Emerging evid

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The Mediating Role of Locus of Control in the Effect of Organizational Justice on Organizational Cynicism in School Organizations

In this study, the mediating role of locus of control in the effect of organizational justice on organizational cynicism in schools was examined.The research started with a orange zinger tomato detailed literature review, and information on the definitions and theories of organizational justice, organizational cynicism and locus of control in the l

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Current clinical utilisation of wearable motion sensors for the assessment of outcome following knee arthroplasty: a scoping review

Objectives Wearable motion sensors are used with increasing frequency in the evaluation of gait, function and physical activity within orthopaedics and sports medicine.The integration of wearable technology into the clinical pathway offers the ability to improve post-operative patient assessment beyond the scope of current, questionnaire-based pati

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